PharmacoDB

Sources

Names Used

17-AAG

Tanespimycin

tanespimycin

PharmacoGx

17-AAG

Database	Identifier
Smiles:	CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
Inchikey:	AYUNIORJHRXIBJ-TXHRRWQRSA-N
Pubchem:	6505803

Database

Identifier

Smiles:

CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC

Inchikey:

AYUNIORJHRXIBJ-TXHRRWQRSA-N

Pubchem:

Top molecular features associated with response to 17-AAG

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF708	GDSC1000	pan-cancer	AAC	-0.27	2e-12
mRNA	ZNF682	CCLE	pan-cancer	AAC	-0.2	5e-05
mRNA	ZNF682	GDSC1000	pan-cancer	AAC	-0.2	4e-09
mRNA	ZNF669	GDSC1000	pan-cancer	AAC	-0.16	9e-07
mRNA	ZNF667	CCLE	pan-cancer	AAC	-0.2	0.0001
mRNA	ZNF667	GDSC1000	pan-cancer	AAC	-0.16	5e-06
mRNA	ZNF646	GDSC1000	pan-cancer	AAC	-0.17	2e-06
mRNA	ZNF639	GDSC1000	pan-cancer	AAC	-0.15	9e-06
mRNA	ZNF611	GDSC1000	pan-cancer	AAC	-0.17	2e-07
mRNA	ZNF610	GDSC1000	pan-cancer	AAC	-0.14	3e-05