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17-AAG

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY17-AAG
FIMMTanespimycin
CTRPv2tanespimycin
PharmacoGx 17-AAG

External IDs

DatabaseIdentifier
Smiles: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
Inchikey: AYUNIORJHRXIBJ-TXHRRWQRSA-N
Pubchem: 6505803

FDA Approval Status

Not Approved
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Top molecular features associated with response to 17-AAG


Feature TypeStandardized
Nominal ANOVA
mRNA HELZ2 GDSC1000 pan-cancer AAC 0.12 0.0001
mRNA SESN3 GDSC1000 pan-cancer AAC -0.12 0.0001
mRNA HSPA5 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA MICAL2 GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA ATOH7 GDSC1000 pan-cancer AAC -0.12 0.0001
mRNA ARAP3 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA KIAA1324 GDSC1000 pan-cancer AAC -0.13 0.0001
mRNA CTGF GDSC1000 pan-cancer AAC 0.15 0.0001
mRNA HAUS5 GDSC1000 pan-cancer AAC -0.13 0.0001
mRNA ZNF606 GDSC1000 pan-cancer AAC -0.13 0.0001
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