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Vorinostat

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMVorinostat
gCSI, CTRPv2vorinostat
PharmacoGx Vorinostat

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
Inchikey: WAEXFXRVDQXREF-UHFFFAOYSA-N
Pubchem: 5311

Annotated Targets

HDAC6, HDAC1, HDAC2, HDAC3, HDAC10, HDAC11, HDAC5, HDAC8, HDAC9

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Vorinostat


Feature TypeStandardized
Nominal ANOVA
mRNA PLK2 GDSC1000 pan-cancer AAC -0.24 6e-09
mRNA MDN1 GDSC1000 pan-cancer AAC 0.2 6e-09
mRNA CCDC77 GDSC1000 pan-cancer AAC 0.19 6e-09
mRNA KLHL23 GDSC1000 pan-cancer AAC 0.2 6e-09
mRNA ARHGAP29 GDSC1000 pan-cancer AAC -0.23 6e-09
mRNA MSI1 CTRPv2 pan-cancer AAC 0.2 6e-09
mRNA MYH9 GDSC1000 pan-cancer AAC -0.2 6e-09
mRNA LY96 GDSC1000 pan-cancer AAC -0.21 6e-09
mRNA FAM161A GDSC1000 pan-cancer AAC 0.19 7e-09
mRNA SALL2 CTRPv2 pan-cancer AAC 0.2 7e-09
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