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Vorinostat

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMVorinostat
gCSI, CTRPv2vorinostat
PharmacoGx Vorinostat

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
Inchikey: WAEXFXRVDQXREF-UHFFFAOYSA-N
Pubchem: 5311

Annotated Targets

HDAC6, HDAC1, HDAC2, HDAC3, HDAC10, HDAC11, HDAC5, HDAC8, HDAC9

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Vorinostat


Feature TypeStandardized
Nominal ANOVA
mRNA FUCA2 GDSC1000 pan-cancer AAC -0.22 3e-09
mRNA NKAIN1 GDSC1000 pan-cancer AAC 0.2 3e-09
mRNA ZNF74 GDSC1000 pan-cancer AAC 0.19 3e-09
mRNA H1FX CTRPv2 pan-cancer AAC 0.2 3e-09
mRNA WASF1 GDSC1000 pan-cancer AAC 0.2 3e-09
mRNA DAZAP1 gCSI pan-cancer AAC 0.32 3e-09
mRNA CD109 GDSC1000 pan-cancer AAC -0.2 3e-09
mRNA SPAST GDSC1000 pan-cancer AAC 0.19 3e-09
mRNA DDX60 gCSI pan-cancer AAC -0.32 3e-09
mRNA LBR GDSC1000 pan-cancer AAC 0.22 4e-09
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