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Vorinostat

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMVorinostat
gCSI, CTRPv2vorinostat
PharmacoGx Vorinostat

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
Inchikey: WAEXFXRVDQXREF-UHFFFAOYSA-N
Pubchem: 5311

Annotated Targets

HDAC6, HDAC1, HDAC2, HDAC3, HDAC10, HDAC11, HDAC5, HDAC8, HDAC9

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Vorinostat


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF77 GDSC1000 pan-cancer AAC 0.12 7e-05
mRNA MUS81 CTRPv2 pan-cancer AAC -0.13 7e-05
mRNA RIPK1 GDSC1000 pan-cancer AAC -0.12 7e-05
mRNA SYP GDSC1000 pan-cancer AAC 0.13 7e-05
mRNA KNOP1 GDSC1000 pan-cancer AAC 0.12 7e-05
mRNA FBXL15 CTRPv2 pan-cancer AAC 0.13 7e-05
mRNA DDX60 GDSC1000 pan-cancer AAC -0.13 7e-05
mRNA HSPA5 GDSC1000 pan-cancer AAC -0.13 7e-05
mRNA CHTF18 GDSC1000 pan-cancer AAC 0.12 7e-05
mRNA RARS GDSC1000 pan-cancer AAC -0.13 7e-05
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