PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ACTN1	GDSC1000	pan-cancer	AAC	0.21	3e-07
mRNA	ACTL6B	GDSC1000	pan-cancer	AAC	-0.22	5e-11
mRNA	ACSS1	GDSC1000	pan-cancer	AAC	-0.14	0.0002
mRNA	ACOT9	GDSC1000	pan-cancer	AAC	0.19	4e-09
mRNA	ACO1	GDSC1000	pan-cancer	AAC	0.15	9e-06
mRNA	ACE	gCSI	pan-cancer	AAC	-0.23	7e-05
mRNA	ACAP3	GDSC1000	pan-cancer	AAC	-0.17	5e-08
mRNA	AC016577.1	CTRPv2	pan-cancer	AAC	-0.17	0.0002
mRNA	AC013461.1	GDSC1000	pan-cancer	AAC	0.14	9e-06
mRNA	AC007326.1	CTRPv2	pan-cancer	AAC	-0.18	0.0001