PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HERPUD2	GDSC1000	pan-cancer	AAC	0.18	8e-09
mRNA	UNC79	GDSC1000	pan-cancer	AAC	-0.19	8e-09
mRNA	NT5E	GDSC1000	pan-cancer	AAC	0.2	9e-09
mRNA	REEP1	GDSC1000	pan-cancer	AAC	-0.19	9e-09
mRNA	ATCAY	GDSC1000	pan-cancer	AAC	-0.2	9e-09
mRNA	GRP	GDSC1000	pan-cancer	AAC	-0.19	9e-09
mRNA	ANXA1	GDSC1000	pan-cancer	AAC	0.21	1e-08
mRNA	MYRIP	GDSC1000	pan-cancer	AAC	-0.19	1e-08
mRNA	TMEM240	GDSC1000	pan-cancer	AAC	-0.18	1e-08
mRNA	HEG1	GDSC1000	pan-cancer	AAC	0.21	1e-08