PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CXXC4	GDSC1000	pan-cancer	AAC	-0.21	4e-10
mRNA	SYP	GDSC1000	pan-cancer	AAC	-0.21	4e-10
mRNA	CTSZ	GDSC1000	pan-cancer	AAC	0.21	4e-10
mRNA	PLAU	GDSC1000	pan-cancer	AAC	0.23	4e-10
mRNA	BAG3	GDSC1000	pan-cancer	AAC	0.24	4e-10
mRNA	EIF2AK4	GDSC1000	pan-cancer	AAC	0.2	4e-10
mRNA	DUSP26	GDSC1000	pan-cancer	AAC	-0.21	4e-10
mRNA	CAV1	GDSC1000	pan-cancer	AAC	0.24	5e-10
mRNA	RUNDC3B	GDSC1000	pan-cancer	AAC	-0.2	5e-10
mRNA	BNC1	GDSC1000	pan-cancer	AAC	0.24	5e-10