PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ACOT9	GDSC1000	pan-cancer	AAC	0.19	4e-09
mRNA	AL513122.2	CTRPv2	pan-cancer	AAC	-0.31	4e-09
mRNA	ST18	GDSC1000	pan-cancer	AAC	-0.19	4e-09
mRNA	TLDC1	GDSC1000	pan-cancer	AAC	0.23	4e-09
mRNA	MYOF	GDSC1000	pan-cancer	AAC	0.25	4e-09
mRNA	IFITM3	GDSC1000	pan-cancer	AAC	0.24	5e-09
mRNA	ATP6V0E2	GDSC1000	pan-cancer	AAC	-0.19	5e-09
mRNA	HES6	GDSC1000	pan-cancer	AAC	-0.19	5e-09
mRNA	ADORA2B	GDSC1000	pan-cancer	AAC	0.22	5e-09
mRNA	FADS3	GDSC1000	pan-cancer	AAC	0.19	5e-09