PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ARHGAP19	gCSI	pan-cancer	AAC	0.24	0.0002
mRNA	UPK3A	gCSI	pan-cancer	AAC	-0.2	0.0002
mRNA	IRAK2	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	RAB11FIP1	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	EPC1	GDSC1000	pan-cancer	AAC	-0.14	0.0002
mRNA	FMO5	GDSC1000	pan-cancer	AAC	-0.12	0.0002
mRNA	OR51D1	gCSI	pan-cancer	AAC	-0.19	0.0002
mRNA	KHSRP	CTRPv2	pan-cancer	AAC	0.2	0.0002
mRNA	PSAP	CTRPv2	pan-cancer	AAC	-0.2	0.0002
mRNA	SNAI3	gCSI	pan-cancer	AAC	-0.23	0.0002