PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TRPC4AP	gCSI	pan-cancer	AAC	-0.27	6e-07
mRNA	GRM8	GDSC1000	pan-cancer	AAC	-0.15	6e-07
mRNA	DACH1	GDSC1000	pan-cancer	AAC	-0.16	6e-07
mRNA	RPF2	gCSI	pan-cancer	AAC	0.26	6e-07
mRNA	SRSF12	GDSC1000	pan-cancer	AAC	-0.19	6e-07
mRNA	E2F2	GDSC1000	pan-cancer	AAC	-0.19	6e-07
mRNA	GPR176	GDSC1000	pan-cancer	AAC	0.18	6e-07
mRNA	RGS10	GDSC1000	pan-cancer	AAC	0.16	7e-07
mRNA	DNAJB13	GDSC1000	pan-cancer	AAC	-0.16	7e-07
mRNA	CTTNBP2	GDSC1000	pan-cancer	AAC	-0.16	7e-07