PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SLC25A43	GDSC1000	pan-cancer	AAC	0.19	5e-09
mRNA	RNF183	GDSC1000	pan-cancer	AAC	-0.18	5e-09
mRNA	TAGLN3	GDSC1000	pan-cancer	AAC	-0.2	6e-09
mRNA	RUFY3	GDSC1000	pan-cancer	AAC	-0.2	6e-09
mRNA	IL1B	GDSC1000	pan-cancer	AAC	0.19	7e-09
mRNA	TBC1D2	GDSC1000	pan-cancer	AAC	0.23	7e-09
mRNA	COL4A1	GDSC1000	pan-cancer	AAC	0.23	7e-09
mRNA	SLC17A4	gCSI	pan-cancer	AAC	-0.31	7e-09
mRNA	LRRC75A	GDSC1000	pan-cancer	AAC	-0.2	8e-09
mRNA	SFT2D1	GDSC1000	pan-cancer	AAC	0.19	8e-09