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Ki8751

Ki8751

Synonyms

Sources	Names Used
CTRPv2	Ki8751
PharmacoGx	Ki8751

External IDs

Database	Identifier
Smiles:	COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)c(F)c3)c2cc1OC
Pubchem:	11317348

Annotated Targets

KDR, KIT, PDGFRA

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Ki8751

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MSH5	CTRPv2	pan-cancer	AAC	0.15	0.0005
mRNA	LARP7	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	TMEM51	CTRPv2	pan-cancer	AAC	-0.14	0.0005
mRNA	DNAJB9	CTRPv2	pan-cancer	AAC	-0.12	0.0005
mRNA	C7orf73	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	CEP57L1	CTRPv2	pan-cancer	AAC	0.12	0.0005
mRNA	MDM4	CTRPv2	pan-cancer	AAC	0.15	0.0005
mRNA	TGS1	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	SF1	CTRPv2	pan-cancer	AAC	0.14	0.0005
mRNA	RPL14	CTRPv2	pan-cancer	AAC	0.14	0.0005

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