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Ki8751

Ki8751

Synonyms

Sources	Names Used
CTRPv2	Ki8751
PharmacoGx	Ki8751

External IDs

Database	Identifier
Smiles:	COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)c(F)c3)c2cc1OC
Pubchem:	11317348

Annotated Targets

KDR, KIT, PDGFRA

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Ki8751

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRSS57	CTRPv2	pan-cancer	AAC	0.39	7e-29
mRNA	GOLGA8M	CTRPv2	pan-cancer	AAC	0.3	2e-18
mRNA	TIFAB	CTRPv2	pan-cancer	AAC	0.3	3e-18
mRNA	PLPPR3	CTRPv2	pan-cancer	AAC	0.31	4e-18
mRNA	DCANP1	CTRPv2	pan-cancer	AAC	0.3	7e-18
mRNA	ITGAL	CTRPv2	pan-cancer	AAC	0.33	1e-17
mRNA	PDGFRA	CTRPv2	pan-cancer	AAC	0.3	1e-17
mRNA	GOLGA8J	CTRPv2	pan-cancer	AAC	0.29	2e-16
mRNA	RP11-231C18.3	CTRPv2	pan-cancer	AAC	0.28	6e-16
mRNA	CFD	CTRPv2	pan-cancer	AAC	0.27	4e-14

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