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Ki8751

Ki8751

Synonyms

Sources	Names Used
CTRPv2	Ki8751
PharmacoGx	Ki8751

External IDs

Database	Identifier
Smiles:	COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)c(F)c3)c2cc1OC
Pubchem:	11317348

Annotated Targets

KDR, KIT, PDGFRA

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Ki8751

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ENY2	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	ZNF428	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	SCUBE1	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	PAGE2	CTRPv2	pan-cancer	AAC	-0.13	0.0003
mRNA	HNRNPA0	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	RNF146	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	NIPSNAP3B	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	PPIP5K2	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	RASGRP2	CTRPv2	pan-cancer	AAC	0.16	0.0003
mRNA	ZNF430	CTRPv2	pan-cancer	AAC	0.15	0.0003

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