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MGCD-265

Synonyms

SourcesNames Used
CTRPv2MGCD-265
PharmacoGx MGCD-265

External IDs

DatabaseIdentifier
Smiles: Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1
Pubchem: 24901704

Annotated Targets

MET, TEK, MST1R, AXL, FLT1, FLT3, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to MGCD-265


Feature TypeStandardized
Nominal ANOVA
mRNA FAM188B CTRPv2 pan-cancer AAC 0.074 0.03
mRNA ST6GALNAC2 CTRPv2 pan-cancer AAC -0.087 0.03
mRNA RP11-15H20.8 CTRPv2 pan-cancer AAC 0.077 0.03
mRNA OVOL1 CTRPv2 pan-cancer AAC -0.088 0.03
mRNA RNF43 CTRPv2 pan-cancer AAC -0.094 0.03
mRNA TLR7 CTRPv2 pan-cancer AAC -0.074 0.03
mRNA LEPR CTRPv2 pan-cancer AAC 0.072 0.03
mRNA EDEM2 CTRPv2 pan-cancer AAC -0.074 0.03
mRNA GRM7 CTRPv2 pan-cancer AAC 0.08 0.03
mRNA PYURF CTRPv2 pan-cancer AAC 0.076 0.03
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