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MGCD-265

Synonyms

SourcesNames Used
CTRPv2MGCD-265
PharmacoGx MGCD-265

External IDs

DatabaseIdentifier
Smiles: Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1
Pubchem: 24901704

Annotated Targets

MET, TEK, MST1R, AXL, FLT1, FLT3, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to MGCD-265


Feature TypeStandardized
Nominal ANOVA
mRNA MED24 CTRPv2 pan-cancer AAC 0.072 0.03
mRNA DEUP1 CTRPv2 pan-cancer AAC 0.072 0.03
mRNA PSTK CTRPv2 pan-cancer AAC 0.075 0.03
mRNA PRR3 CTRPv2 pan-cancer AAC 0.084 0.03
mRNA LIMD2 CTRPv2 pan-cancer AAC 0.1 0.03
mRNA ARFGEF1 CTRPv2 pan-cancer AAC 0.073 0.03
mRNA TADA2A CTRPv2 pan-cancer AAC 0.077 0.03
mRNA XXbac-BPG32J3.19 CTRPv2 pan-cancer AAC -0.076 0.03
mRNA FOXO4 CTRPv2 pan-cancer AAC 0.076 0.03
mRNA LAMA5 CTRPv2 pan-cancer AAC -0.084 0.03
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