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OSI-930

OSI-930

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	OSI-930
PharmacoGx	OSI-930

External IDs

Database	Identifier
Smiles:	FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1
Pubchem:	9868037

Annotated Targets

KIT, KDR, FLT1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to OSI-930

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GNA15	CTRPv2	pan-cancer	AAC	0.2	3e-07
mRNA	TAF5L	CTRPv2	pan-cancer	AAC	0.19	3e-07
mRNA	CCAR2	CTRPv2	pan-cancer	AAC	0.2	3e-07
mRNA	CISH	CTRPv2	pan-cancer	AAC	0.19	3e-07
mRNA	NUP54	CTRPv2	pan-cancer	AAC	0.18	3e-07
mRNA	C1QTNF4	GDSC1000	pan-cancer	AAC	0.17	3e-07
mRNA	VRK1	CTRPv2	pan-cancer	AAC	0.21	3e-07
mRNA	AGPAT5	CTRPv2	pan-cancer	AAC	0.19	4e-07
mRNA	PPP1R27	GDSC1000	pan-cancer	AAC	0.17	4e-07
mRNA	PRPF38A	CTRPv2	pan-cancer	AAC	0.2	4e-07

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