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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA GRAP CTRPv2 pan-cancer AAC 0.19 6e-06
mRNA INPP1 GDSC1000 pan-cancer AAC -0.16 6e-06
mRNA DTNBP1 GDSC1000 pan-cancer AAC 0.16 6e-06
mRNA POPDC3 GDSC1000 pan-cancer AAC -0.15 6e-06
mRNA DNTT GDSC1000 pan-cancer AAC 0.14 6e-06
mRNA PRKCB GDSC1000 pan-cancer AAC 0.18 7e-06
mRNA GRAP2 CTRPv2 pan-cancer AAC -0.17 7e-06
mRNA GTF2I CTRPv2 pan-cancer AAC 0.16 7e-06
mRNA NLRP7 CTRPv2 pan-cancer AAC 0.16 8e-06
mRNA ZCCHC7 GDSC1000 pan-cancer AAC 0.17 9e-06
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