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ZSTK474

ZSTK474

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	ZSTK474
PharmacoGx	ZSTK474

External IDs

Database	Identifier
Smiles:	FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem:	11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ZSTK474

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CD72	GDSC1000	pan-cancer	AAC	0.18	3e-07
mRNA	CD79B	GDSC1000	pan-cancer	AAC	0.19	4e-07
mRNA	ZNF232	GDSC1000	pan-cancer	AAC	0.16	4e-07
mRNA	CCAR1	GDSC1000	pan-cancer	AAC	0.17	4e-07
mRNA	HVCN1	GDSC1000	pan-cancer	AAC	0.21	4e-07
mRNA	NQO1	GDSC1000	pan-cancer	AAC	-0.2	5e-07
mRNA	CD19	GDSC1000	pan-cancer	AAC	0.18	5e-07
mRNA	CD53	GDSC1000	pan-cancer	AAC	0.33	5e-07
mRNA	PIK3CG	GDSC1000	pan-cancer	AAC	0.23	5e-07
mRNA	HVCN1	CTRPv2	pan-cancer	AAC	0.21	6e-07

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