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TPCA-1

TPCA-1

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	TPCA-1
PharmacoGx	TPCA-1

External IDs

Database	Identifier
Smiles:	NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2
Pubchem:	9903786

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TPCA-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	UGT3A2	GDSC1000	pan-cancer	AAC	0.17	4e-07
mRNA	RPUSD2	GDSC1000	pan-cancer	AAC	0.16	4e-07
mRNA	ITGB5	GDSC1000	pan-cancer	AAC	-0.18	4e-07
mRNA	ZNF84	GDSC1000	pan-cancer	AAC	0.15	5e-07
mRNA	P4HA2	GDSC1000	pan-cancer	AAC	-0.18	6e-07
mRNA	TRMT10C	GDSC1000	pan-cancer	AAC	0.15	6e-07
mRNA	FAM174A	GDSC1000	pan-cancer	AAC	-0.15	6e-07
mRNA	ARHGEF6	GDSC1000	pan-cancer	AAC	0.19	7e-07
mRNA	ELF2	GDSC1000	pan-cancer	AAC	0.16	8e-07
mRNA	ARFGEF2	CTRPv2	pan-cancer	AAC	-0.16	9e-07

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