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SB-431542

SB-431542

Synonyms

Sources	Names Used
CTRPv2	SB-431542
PharmacoGx	SB-431542

External IDs

Database	Identifier
Smiles:	NC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccccn3)c4ccc5OCOc5c4
Pubchem:	4521392

Annotated Targets

ACVR1C, TGFBR1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB-431542

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PAPPA2	CTRPv2	pan-cancer	AAC	0.067	0.07
mRNA	CDK10	CTRPv2	pan-cancer	AAC	-0.068	0.07
mRNA	ACADM	CTRPv2	pan-cancer	AAC	-0.076	0.07
mRNA	OLR1	CTRPv2	pan-cancer	AAC	-0.068	0.07
mRNA	TMEM86A	CTRPv2	pan-cancer	AAC	0.07	0.07
mRNA	KIF1B	CTRPv2	pan-cancer	AAC	0.075	0.07
mRNA	TRMT112	CTRPv2	pan-cancer	AAC	-0.067	0.07
mRNA	HOXD9	CTRPv2	pan-cancer	AAC	0.071	0.07
mRNA	TDRD3	CTRPv2	pan-cancer	AAC	-0.07	0.07
mRNA	SLCO3A1	CTRPv2	pan-cancer	AAC	0.068	0.07

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