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SB-431542

SB-431542

Synonyms

Sources	Names Used
CTRPv2	SB-431542
PharmacoGx	SB-431542

External IDs

Database	Identifier
Smiles:	NC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccccn3)c4ccc5OCOc5c4
Pubchem:	4521392

Annotated Targets

ACVR1C, TGFBR1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SB-431542

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	BAMBI	CTRPv2	pan-cancer	AAC	0.073	0.07
mRNA	DNAJC5B	CTRPv2	pan-cancer	AAC	0.067	0.07
mRNA	GJA3	CTRPv2	pan-cancer	AAC	-0.069	0.07
mRNA	NDUFC2	CTRPv2	pan-cancer	AAC	0.066	0.07
mRNA	TIPARP	CTRPv2	pan-cancer	AAC	0.07	0.07
mRNA	AKAP14	CTRPv2	pan-cancer	AAC	0.067	0.07
mRNA	BIRC5	CTRPv2	pan-cancer	AAC	-0.069	0.07
mRNA	SLC22A31	CTRPv2	pan-cancer	AAC	-0.067	0.07
mRNA	GLTP	CTRPv2	pan-cancer	AAC	-0.073	0.07
mRNA	VWA5A	CTRPv2	pan-cancer	AAC	0.067	0.07

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