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UNC0638

UNC0638

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	UNC0638
PharmacoGx	UNC0638

External IDs

Database	Identifier
Smiles:	CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
Inchikey:	QOECJCJVIMVJGX-UHFFFAOYSA-N
Pubchem:	46224516

Annotated Targets

EHMT1, EHMT2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to UNC0638

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	EPB41	GDSC1000	pan-cancer	AAC	0.17	3e-07
mRNA	PLCE1	GDSC1000	pan-cancer	AAC	-0.16	3e-07
mRNA	SUCLG2	GDSC1000	pan-cancer	AAC	-0.16	3e-07
mRNA	CERK	GDSC1000	pan-cancer	AAC	0.16	4e-07
mRNA	TUBA3D	CTRPv2	pan-cancer	AAC	0.19	4e-07
mRNA	PAK5	GDSC1000	pan-cancer	AAC	0.16	4e-07
mRNA	FOXN3	CTRPv2	pan-cancer	AAC	0.19	5e-07
mRNA	DISP3	CTRPv2	pan-cancer	AAC	0.18	5e-07
mRNA	SBK1	CTRPv2	pan-cancer	AAC	0.19	5e-07
mRNA	FAM117B	CTRPv2	pan-cancer	AAC	0.19	5e-07

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