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UNC0638

Synonyms

SourcesNames Used
GDSC1000, CTRPv2UNC0638
PharmacoGx UNC0638

External IDs

DatabaseIdentifier
Smiles: CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
Inchikey: QOECJCJVIMVJGX-UHFFFAOYSA-N
Pubchem: 46224516

Annotated Targets

EHMT1, EHMT2

FDA Approval Status

Not Approved
Number of cell lines tested with UNC0638(per dataset)01002003004005006007008009001k# cell lines CCLEgCSIGRAYFIMMUHNBreastCTRPv2GDSC1000000008301047
Number of tissues tested with UNC0638(per dataset)05101520253035# tissues CCLEgCSIGRAYFIMMUHNBreastCTRPv2GDSC1000000002535
Dataset Select
UNC0638: AACAAC0.000.050.100.150.200.250.300.350.400.450.500.55MY-M12MY-M12BC-2BC-2JSC-1JSC-1KP-N-YSKP-N-YSCOR-L303COR-L303SU-DHL-5SU-DHL-5NCI-H748NCI-H748P30-OHKP30-OHKKARPAS-45KARPAS-45HuT 78HuT 78DND-41DND-41ES5ES5CHP-134CHP-134ETK-1ETK-1EW7476EW7476NCI-H865NCI-H865IST-SL1IST-SL1NCI-H2596NCI-H2596MOLP-8MOLP-8BC-3BC-3H2731H2731MKL-2MKL-2BT147BT147CCRF-CEMCCRF-CEMLU-139LU-139HHHHSBC-1SBC-1TE 441.TTE 441.TMHH-PREB-1MHH-PREB-1PA-1PA-1 SW620SW620NCI-H1623NCI-H1623D-283MEDD-283MEDhuH-1huH-1KP-4KP-4Hs-578-THs-578-TNCI-H1155NCI-H1155SNU-1066SNU-1066BT145BT145DIFIDIFINCI-H2286NCI-H2286CL-34CL-34KMBC-2KMBC-2SK-UT-1SK-UT-1LMSULMSUBT224BT224DJM-1DJM-1EKVXEKVXBOKUBOKUNCI-H820NCI-H820PWR-1EPWR-1EGeoGeoDLD-1DLD-1HEC-50BHEC-50BBT179BT179T3M-10T3M-10BT164BT164Gp2DGp2DJHOM-1JHOM-1JHUEM-7JHUEM-7MY-M12BC-2JSC-1KP-N-YSCOR-L303SU-DHL-5NCI-H748P30-OHKKARPAS-45HuT 78DND-41ES5CHP-134ETK-1EW7476NCI-H865IST-SL1NCI-H2596MOLP-8BC-3H2731MKL-2BT147CCRF-CEMLU-139HHSBC-1TE 441.TMHH-PREB-1PA-1 SW620NCI-H1623D-283MEDhuH-1KP-4Hs-578-TNCI-H1155SNU-1066BT145DIFINCI-H2286CL-34KMBC-2SK-UT-1LMSUBT224DJM-1EKVXBOKUNCI-H820PWR-1EGeoDLD-1HEC-50BBT179T3M-10BT164Gp2DJHOM-1JHUEM-7MY-M12: 0.55Synonyms: MY-M12BC-2: 0.48Synonyms: BC-2JSC-1: 0.48Synonyms: JSC-1KP-N-YS: 0.46Synonyms: KP-N-YSCOR-L303: 0.39Synonyms: COR-L303SU-DHL-5: 0.38Synonyms: SU-DHL-5NCI-H748: 0.37Synonyms: NCI-H748P30-OHK: 0.37Synonyms: P30-OHKKARPAS-45: 0.37Synonyms: KARPAS-45HuT 78: 0.36Synonyms: HuT 78, HuT_78, HUT78DND-41: 0.36Synonyms: DND-41, DND41ES5: 0.35Synonyms: ES5CHP-134: 0.35Synonyms: CHP-134ETK-1: 0.34Synonyms: ETK-1EW7476: 0.33Synonyms: EW7476NCI-H865: 0.33Synonyms: NCI-H865IST-SL1: 0.33Synonyms: IST-SL1NCI-H2596: 0.33Synonyms: NCI-H2596MOLP-8: 0.32Synonyms: MOLP-8, MOLP8BC-3: 0.32Synonyms: BC-3H2731: 0.31Synonyms: H2731MKL-2: 0.31Synonyms: MKL-2BT147: 0.31Synonyms: BT147CCRF-CEM: 0.31Synonyms: CCRF-CEM, CCRFCEMLU-139: 0.31Synonyms: LU-139HH: 0.31Synonyms: HHSBC-1: 0.31Synonyms: SBC-1TE 441.T: 0.31Synonyms: TE 441.T, TE_441.T, TE-441-T, TE441TMHH-PREB-1: 0.30Synonyms: MHH-PREB-1PA-1: 0.30Synonyms: PA-1 : 0.00Synonyms: : 0.00Synonyms: : 0.00Synonyms: : 0.00Synonyms: : 0.00Synonyms: SW620: 0.00Synonyms: SW620, SW 620NCI-H1623: 0.00Synonyms: NCI-H1623, NCIH1623D-283MED: 0.00Synonyms: D-283MED, D283 Med, D283_Med, D283MEDhuH-1: 0.00Synonyms: huH-1, HUH1KP-4: 0.00Synonyms: KP-4, KP4Hs-578-T: 0.00Synonyms: Hs-578-T, Hs 578T, Hs_578T, HS578T, hs578tNCI-H1155: 0.00Synonyms: NCI-H1155, NCIH1155SNU-1066: 0.00Synonyms: SNU-1066, SNU1066BT145: 0.00Synonyms: BT145DIFI: 0.00Synonyms: DIFINCI-H2286: 0.00Synonyms: NCI-H2286, NCIH2286CL-34: 0.00Synonyms: CL-34, CL34KMBC-2: 0.00Synonyms: KMBC-2, KMBC2SK-UT-1: 0.00Synonyms: SK-UT-1, SKUT1LMSU: 0.00Synonyms: LMSUBT224: 0.00Synonyms: BT224DJM-1: 0.00Synonyms: DJM-1EKVX: 0.00Synonyms: EKVXBOKU: 0.00Synonyms: BOKUNCI-H820: 0.00Synonyms: NCI-H820PWR-1E: 0.00Synonyms: PWR-1EGeo: 0.00Synonyms: GeoDLD-1: 0.00Synonyms: DLD-1, DLD1HEC-50B: 0.00Synonyms: HEC-50B, HEC50BBT179: 0.00Synonyms: BT179T3M-10: 0.00Synonyms: T3M-10, T3M10BT164: 0.00Synonyms: BT164Gp2D: 0.00Synonyms: Gp2D, GP2d, GP2DJHOM-1: 0.00Synonyms: JHOM-1, JHOM1JHUEM-7: 0.00Synonyms: JHUEM-7, JHUEM70.002.004.006.008.0010.0012.0014.00T98GT98GKMM-1KMM-1FU-OV-1FU-OV-1NCI-H1339NCI-H1339BT320BT320SNU-1076SNU-1076SK-HEP-1SK-HEP-1TE-15TE-15PLC-PRF-5PLC-PRF-5NCI-H1993NCI-H1993VM-CUB-1VM-CUB-1VMRC-RCZVMRC-RCZHSC-2HSC-2UM-UC-3UM-UC-3HOSHOSPE/CA-PJ49PE/CA-PJ49CAMA-1CAMA-1A431A431DU-145DU-145D-263MGD-263MGNCI-H1373NCI-H1373Panc 05.04Panc 05.04Caki-2Caki-2SNU-668SNU-668JHOC-5JHOC-5CAL-54CAL-54BB49-HNCBB49-HNCH513H513CAL-62CAL-62NCI-H1869NCI-H1869 Hs 729Hs 729ToledoToledoJSC-1JSC-1IST-SL1IST-SL1PEERPEERBC-2BC-2SW579SW579MOLP-8MOLP-8MOTN-1MOTN-1COV644COV644DND-41DND-41TE 617.TTE 617.TRPMI-8402RPMI-8402EoL-1-cellEoL-1-cellNCI-H1417NCI-H1417OCI-LY10OCI-LY10ES5ES5ETK-1ETK-1KARPAS-45KARPAS-45P30-OHKP30-OHKDOHH-2DOHH-2NALM-6NALM-6SU-DHL-5SU-DHL-5Ki-JKKi-JKHs 611.THs 611.TMY-M12MY-M12A673A673CRO-AP3CRO-AP3Hs 888.THs 888.THuT 78HuT 78T98GKMM-1FU-OV-1NCI-H1339BT320SNU-1076SK-HEP-1TE-15PLC-PRF-5NCI-H1993VM-CUB-1VMRC-RCZHSC-2UM-UC-3HOSPE/CA-PJ49CAMA-1A431DU-145D-263MGNCI-H1373Panc 05.04Caki-2SNU-668JHOC-5CAL-54BB49-HNCH513CAL-62NCI-H1869 Hs 729ToledoJSC-1IST-SL1PEERBC-2SW579MOLP-8MOTN-1COV644DND-41TE 617.TRPMI-8402EoL-1-cellNCI-H1417OCI-LY10ES5ETK-1KARPAS-45P30-OHKDOHH-2NALM-6SU-DHL-5Ki-JKHs 611.TMY-M12A673CRO-AP3Hs 888.THuT 78T98G: 15.71 (log10 µM)Synonyms: T98GKMM-1: 9.16 (log10 µM)Synonyms: KMM-1, KMM1FU-OV-1: 7.51 (log10 µM)Synonyms: FU-OV-1, FUOV1NCI-H1339: 6.85 (log10 µM)Synonyms: NCI-H1339, NCIH1339BT320: 5.79 (log10 µM)Synonyms: BT320SNU-1076: 5.43 (log10 µM)Synonyms: SNU-1076, SNU1076SK-HEP-1: 4.60 (log10 µM)Synonyms: SK-HEP-1, SKHEP1TE-15: 4.47 (log10 µM)Synonyms: TE-15, TE15PLC-PRF-5: 4.13 (log10 µM)Synonyms: PLC-PRF-5, PLC/PRF/5, PLC_PRF_5, PLCPRF5NCI-H1993: 4.03 (log10 µM)Synonyms: NCI-H1993VM-CUB-1: 3.89 (log10 µM)Synonyms: VM-CUB-1, VM-CUB1, VMCUB1VMRC-RCZ: 3.67 (log10 µM)Synonyms: VMRC-RCZ, VMRCRCZHSC-2: 3.61 (log10 µM)Synonyms: HSC-2, HSC2UM-UC-3: 3.59 (log10 µM)Synonyms: UM-UC-3, UMUC3HOS: 3.53 (log10 µM)Synonyms: HOSPE/CA-PJ49: 3.50 (log10 µM)Synonyms: PE/CA-PJ49, PE_CA-PJ49, PECAPJ49CAMA-1: 3.48 (log10 µM)Synonyms: CAMA-1, CAMA1, cama1A431: 3.33 (log10 µM)Synonyms: A431, A-431DU-145: 3.24 (log10 µM)Synonyms: DU-145, DU 145, DU_145, DU145D-263MG: 3.22 (log10 µM)Synonyms: D-263MGNCI-H1373: 2.80 (log10 µM)Synonyms: NCI-H1373, NCIH1373Panc 05.04: 2.78 (log10 µM)Synonyms: Panc 05.04, Panc_05.04, PANC0504Caki-2: 2.70 (log10 µM)Synonyms: Caki-2, CAKI2SNU-668: 2.64 (log10 µM)Synonyms: SNU-668, SNU668JHOC-5: 2.58 (log10 µM)Synonyms: JHOC-5, JHOC5CAL-54: 2.47 (log10 µM)Synonyms: CAL-54, CAL 54, CAL54BB49-HNC: 2.46 (log10 µM)Synonyms: BB49-HNCH513: 2.44 (log10 µM)Synonyms: H513CAL-62: 2.41 (log10 µM)Synonyms: CAL-62, CAL62NCI-H1869: 2.37 (log10 µM)Synonyms: NCI-H1869, NCIH1869 : 0.00 (log10 µM)Synonyms: : 0.00 (log10 µM)Synonyms: : 0.00 (log10 µM)Synonyms: : 0.00 (log10 µM)Synonyms: : 0.00 (log10 µM)Synonyms: Hs 729: 0.45 (log10 µM)Synonyms: Hs 729, Hs_729, HS729Toledo: 0.45 (log10 µM)Synonyms: Toledo, TOLEDOJSC-1: 0.45 (log10 µM)Synonyms: JSC-1IST-SL1: 0.45 (log10 µM)Synonyms: IST-SL1PEER: 0.45 (log10 µM)Synonyms: PEERBC-2: 0.45 (log10 µM)Synonyms: BC-2SW579: 0.44 (log10 µM)Synonyms: SW579MOLP-8: 0.44 (log10 µM)Synonyms: MOLP-8, MOLP8MOTN-1: 0.43 (log10 µM)Synonyms: MOTN-1, MOTN1COV644: 0.43 (log10 µM)Synonyms: COV644DND-41: 0.42 (log10 µM)Synonyms: DND-41, DND41TE 617.T: 0.41 (log10 µM)Synonyms: TE 617.T, TE_617.T, TE617TRPMI-8402: 0.41 (log10 µM)Synonyms: RPMI-8402, RPMI8402EoL-1-cell: 0.41 (log10 µM)Synonyms: EoL-1-cell, EOL-1, EOL1NCI-H1417: 0.39 (log10 µM)Synonyms: NCI-H1417OCI-LY10: 0.39 (log10 µM)Synonyms: OCI-LY10, OCI-LY-10, OCILY10ES5: 0.38 (log10 µM)Synonyms: ES5ETK-1: 0.36 (log10 µM)Synonyms: ETK-1KARPAS-45: 0.35 (log10 µM)Synonyms: KARPAS-45P30-OHK: 0.33 (log10 µM)Synonyms: P30-OHKDOHH-2: 0.32 (log10 µM)Synonyms: DOHH-2, DOHH2NALM-6: 0.31 (log10 µM)Synonyms: NALM-6, NALM6SU-DHL-5: 0.31 (log10 µM)Synonyms: SU-DHL-5Ki-JK: 0.31 (log10 µM)Synonyms: Ki-JK, KIJKHs 611.T: 0.29 (log10 µM)Synonyms: Hs 611.T, Hs_611.T, HS611TMY-M12: 0.24 (log10 µM)Synonyms: MY-M12A673: 0.23 (log10 µM)Synonyms: A673, A-673CRO-AP3: 0.21 (log10 µM)Synonyms: CRO-AP3Hs 888.T: 0.16 (log10 µM)Synonyms: Hs 888.T, Hs_888.T, HS888THuT 78: 0.13 (log10 µM)Synonyms: HuT 78, HuT_78, HUT78AACpIC50* Plot represents the top and bottom 30 data points** Error Bars represent the Median Absolute Deviation
Download Data as CSV
UNC0638: AACAACTissues0.000.050.100.150.200.250.300.350.400.450.500.55placentaplacentaendometriumendometriumadrenal_glandadrenal_glandoral_cavityoral_cavitybiliary_tractbiliary_tractkidneykidneylarge_intestinelarge_intestinecervixcervixpancreaspancreasupper_aerodigestive_tractupper_aerodigestive_tractprostateprostateurinary_tracturinary_tractthyroidthyroidoesophagusoesophagusliverliverbreastbreastskinskinstomachstomachovaryovarymiscmiscpleurapleuraotherotherlunglungvulvavulvaautonomic_gangliaautonomic_gangliacentral_nervous_systemcentral_nervous_systemsoft_tissuesoft_tissueunknownunknownhead_and_neckhead_and_neckbonebonehaematopoietic_and_lymphoid_tissuehaematopoietic_and_lymphoid_tissuesmall_intestinesmall_intestineneuroblastomaneuroblastomatestistestisgastrointestinal_tract_(site_indeterminate)gastrointestinal_tract_(site_indeterminate)salivary_glandsalivary_gland0.000.200.400.600.801.001.201.401.601.80neuroblastomaneuroblastomasmall_intestinesmall_intestineplacentaplacentamiscmischaematopoietic_and_lymphoid_tissuehaematopoietic_and_lymphoid_tissuebonebonebiliary_tractbiliary_tractcervixcervixotherotherautonomic_gangliaautonomic_gangliatestistestisoral_cavityoral_cavityhead_and_neckhead_and_neckbreastbreastkidneykidneyunknownunknownsoft_tissuesoft_tissueprostateprostateskinskincentral_nervous_systemcentral_nervous_systemlunglunglarge_intestinelarge_intestinegastrointestinal_tract_(site_indeterminate)gastrointestinal_tract_(site_indeterminate)stomachstomachliverliverpleurapleurapancreaspancreasoesophagusoesophagusovaryovarythyroidthyroidupper_aerodigestive_tractupper_aerodigestive_tractvulvavulvaurinary_tracturinary_tractendometriumendometriumadrenal_glandadrenal_glandsalivary_glandsalivary_glandAACpIC50= Truncated outliers