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MLN4924

MLN4924

Synonyms

Sources	Names Used
GDSC1000, GRAY	MLN4924
CTRPv2	pevonedistat
PharmacoGx	MLN4924

External IDs

Database	Identifier
Smiles:	C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
Inchikey:	MPUQHZXIXSTTDU-ZIODWWTISA-N
Pubchem:	71729979

FDA Approval Status

Not Approved

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Top molecular features associated with response to MLN4924

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KIF15	CTRPv2	pan-cancer	AAC	0.19	4e-07
mRNA	RAD54L	CTRPv2	pan-cancer	AAC	0.18	5e-07
mRNA	SRSF1	CTRPv2	pan-cancer	AAC	0.18	5e-07
mRNA	PPP1CC	CTRPv2	pan-cancer	AAC	0.17	5e-07
mRNA	NASP	CTRPv2	pan-cancer	AAC	0.17	5e-07
mRNA	NSMAF	GDSC1000	pan-cancer	AAC	0.21	5e-07
mRNA	KIAA0101	CTRPv2	pan-cancer	AAC	0.18	5e-07
mRNA	EIF3E	CTRPv2	pan-cancer	AAC	0.18	5e-07
mRNA	YIPF5	CTRPv2	pan-cancer	AAC	-0.2	6e-07
mRNA	HNRNPA1L2	CTRPv2	pan-cancer	AAC	0.2	6e-07

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