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MLN4924

MLN4924

Synonyms

Sources	Names Used
GDSC1000, GRAY	MLN4924
CTRPv2	pevonedistat
PharmacoGx	MLN4924

External IDs

Database	Identifier
Smiles:	C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
Inchikey:	MPUQHZXIXSTTDU-ZIODWWTISA-N
Pubchem:	71729979

FDA Approval Status

Not Approved

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Top molecular features associated with response to MLN4924

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RPS9	CTRPv2	pan-cancer	AAC	0.2	2e-07
mRNA	KNTC1	CTRPv2	pan-cancer	AAC	0.19	2e-07
mRNA	CEP295NL	CTRPv2	pan-cancer	AAC	-0.22	2e-07
mRNA	ANP32A	CTRPv2	pan-cancer	AAC	0.2	2e-07
mRNA	TYW3	CTRPv2	pan-cancer	AAC	0.18	2e-07
mRNA	DAAM1	GDSC1000	pan-cancer	AAC	-0.21	2e-07
mRNA	HDAC2	CTRPv2	pan-cancer	AAC	0.18	2e-07
mRNA	DDX39B	CTRPv2	pan-cancer	AAC	0.18	2e-07
mRNA	ATP6V0E1	CTRPv2	pan-cancer	AAC	-0.2	2e-07
mRNA	RPL18	CTRPv2	pan-cancer	AAC	0.19	3e-07

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