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MLN4924

MLN4924

Synonyms

Sources	Names Used
GDSC1000, GRAY	MLN4924
CTRPv2	pevonedistat
PharmacoGx	MLN4924

External IDs

Database	Identifier
Smiles:	C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=O)N
Inchikey:	MPUQHZXIXSTTDU-ZIODWWTISA-N
Pubchem:	71729979

FDA Approval Status

Not Approved

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Top molecular features associated with response to MLN4924

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MSH5-SAPCD1	CTRPv2	pan-cancer	AAC	0.2	8e-07
mRNA	MAGED2	CTRPv2	pan-cancer	AAC	-0.19	8e-07
mRNA	MAP3K7	GDSC1000	pan-cancer	AAC	0.2	8e-07
mRNA	RPF1	CTRPv2	pan-cancer	AAC	0.16	9e-07
mRNA	LSM11	CTRPv2	pan-cancer	AAC	0.18	9e-07
mRNA	WDR76	CTRPv2	pan-cancer	AAC	0.18	9e-07
mRNA	ZFP64	GDSC1000	pan-cancer	AAC	0.2	9e-07
mRNA	CDC7	CTRPv2	pan-cancer	AAC	0.18	9e-07
mRNA	RRM2	CTRPv2	pan-cancer	AAC	0.17	1e-06
mRNA	MMS22L	CTRPv2	pan-cancer	AAC	0.17	1e-06

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