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Tamoxifen

Synonyms

SourcesNames Used
GDSC1000, GRAYTamoxifen
CTRPv2tamoxifen
PharmacoGx Tamoxifen

External IDs

DatabaseIdentifier
Smiles: [H+].[H+].[H+].CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O
Inchikey: FQZYTYWMLGAPFJ-OQKDUQJOSA-N
Pubchem: 25010734

Annotated Targets

EBP, ESR1, ESR2, GPER1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCI, PRKCQ, PRKCZ

FDA Approval Status

Approved
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Top molecular features associated with response to Tamoxifen


Feature TypeStandardized
Nominal ANOVA
mRNA TG CTRPv2 pan-cancer AAC 0.21 6e-09
mRNA TPO CTRPv2 pan-cancer AAC 0.21 2e-08
mRNA SST CTRPv2 pan-cancer AAC 0.2 4e-08
mRNA CDC20B GDSC1000 pan-cancer AAC 0.18 6e-08
mRNA GPR83 GDSC1000 pan-cancer AAC 0.18 1e-07
mRNA ADAMTS10 CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA DIO1 CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA RDH10 CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA SYNPO CTRPv2 pan-cancer AAC 0.19 7e-06
mRNA ATOH1 GDSC1000 pan-cancer AAC 0.15 8e-06
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