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Tamoxifen

Synonyms

SourcesNames Used
GDSC1000, GRAYTamoxifen
CTRPv2tamoxifen
PharmacoGx Tamoxifen

External IDs

DatabaseIdentifier
Smiles: [H+].[H+].[H+].CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O
Inchikey: FQZYTYWMLGAPFJ-OQKDUQJOSA-N
Pubchem: 25010734

Annotated Targets

EBP, ESR1, ESR2, GPER1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCI, PRKCQ, PRKCZ

FDA Approval Status

Approved
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Top molecular features associated with response to Tamoxifen


Feature TypeStandardized
Nominal ANOVA
mRNA DRG2 CTRPv2 pan-cancer AAC 0.078 0.04
mRNA RASSF8 GDSC1000 pan-cancer AAC -0.077 0.04
mRNA ZBBX GDSC1000 pan-cancer AAC 0.069 0.04
mRNA CSF2RB GDSC1000 pan-cancer AAC -0.093 0.04
mRNA DGKA CTRPv2 pan-cancer AAC 0.084 0.04
mRNA RPH3A GDSC1000 pan-cancer AAC -0.07 0.04
mRNA ZDHHC13 GDSC1000 pan-cancer AAC 0.072 0.04
mRNA C17orf47 CTRPv2 pan-cancer AAC 0.08 0.04
mRNA ERBB4 GDSC1000 pan-cancer AAC 0.072 0.04
mRNA XRCC4 GDSC1000 pan-cancer AAC 0.071 0.04
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