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Tamoxifen

Synonyms

SourcesNames Used
GDSC1000, GRAYTamoxifen
CTRPv2tamoxifen
PharmacoGx Tamoxifen

External IDs

DatabaseIdentifier
Smiles: [H+].[H+].[H+].CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O
Inchikey: FQZYTYWMLGAPFJ-OQKDUQJOSA-N
Pubchem: 25010734

Annotated Targets

EBP, ESR1, ESR2, GPER1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCI, PRKCQ, PRKCZ

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Tamoxifen


Feature TypeStandardized
Nominal ANOVA
mRNA PTCD2 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA MEP1B GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA C9orf92 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA LCN2 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA GIN1 GDSC1000 pan-cancer AAC 0.12 0.0002
mRNA BBS9 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA KRBOX4 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA DEFB4B CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA RBM41 GDSC1000 pan-cancer AAC 0.12 0.0003
mRNA TBC1D19 GDSC1000 pan-cancer AAC 0.13 0.0003
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