5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MEA1	CTRPv2	pan-cancer	AAC	-0.15	3e-05
mRNA	MIGA1	CTRPv2	pan-cancer	AAC	-0.15	0.0002
mRNA	AC004076.9	CTRPv2	pan-cancer	AAC	-0.15	3e-05
mRNA	ZNF726	CTRPv2	pan-cancer	AAC	-0.15	5e-05
mRNA	TNFRSF12A	CTRPv2	pan-cancer	AAC	-0.15	0.0004
mRNA	VEGFB	CTRPv2	pan-cancer	AAC	-0.15	3e-05
mRNA	OPHN1	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	SOX10	CTRPv2	pan-cancer	AAC	-0.14	0.009
mRNA	TIMP2	CTRPv2	pan-cancer	AAC	-0.14	0.0004
mRNA	EVA1A	CTRPv2	pan-cancer	AAC	-0.14	0.0002

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