5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF665	CTRPv2	pan-cancer	AAC	-0.1	0.004
mRNA	ZNF677	CTRPv2	pan-cancer	AAC	-0.11	0.003
mRNA	ZNF681	CTRPv2	pan-cancer	AAC	-0.13	0.0002
mRNA	ZNF692	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	ZNF701	CTRPv2	pan-cancer	AAC	-0.088	0.01
mRNA	ZNF708	CTRPv2	pan-cancer	AAC	-0.097	0.007
mRNA	ZNF726	CTRPv2	pan-cancer	AAC	-0.15	5e-05
mRNA	ZNF750	CTRPv2	pan-cancer	AAC	0.095	0.009
mRNA	ZNF75A	CTRPv2	pan-cancer	AAC	-0.089	0.01
mRNA	ZNF765	CTRPv2	pan-cancer	AAC	-0.091	0.008

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