5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TRIM35	CTRPv2	pan-cancer	AAC	0.18	2e-06
mRNA	CKMT1B	CTRPv2	pan-cancer	AAC	0.18	1e-06
mRNA	GPR132	CTRPv2	pan-cancer	AAC	0.18	3e-07
mRNA	EEF2	CTRPv2	pan-cancer	AAC	0.18	1e-06
mRNA	RPL7	CTRPv2	pan-cancer	AAC	0.19	2e-07
mRNA	HAND2	CTRPv2	pan-cancer	AAC	0.19	0.02
mRNA	RPL14	CTRPv2	pan-cancer	AAC	0.19	9e-07
mRNA	VWA8	CTRPv2	pan-cancer	AAC	0.19	9e-08
mRNA	QARS	CTRPv2	pan-cancer	AAC	0.19	2e-06
mRNA	WAS	CTRPv2	pan-cancer	AAC	0.19	0.002

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