5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CKMT1A	CTRPv2	pan-cancer	AAC	0.18	3e-06
mRNA	FMNL1	CTRPv2	pan-cancer	AAC	0.18	5e-05
mRNA	MTHFD2	CTRPv2	pan-cancer	AAC	0.18	9e-07
mRNA	HCK	CTRPv2	pan-cancer	AAC	0.18	2e-07
mRNA	IL2RA	CTRPv2	pan-cancer	AAC	0.18	4e-08
mRNA	RPS6KA1	CTRPv2	pan-cancer	AAC	0.18	5e-06
mRNA	GOLGA8M	CTRPv2	pan-cancer	AAC	0.18	4e-08
mRNA	PDE1B	CTRPv2	pan-cancer	AAC	0.18	5e-06
mRNA	HNRNPA1	CTRPv2	pan-cancer	AAC	0.18	3e-06
mRNA	LAD1	CTRPv2	pan-cancer	AAC	0.18	9e-06

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