5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF524	CTRPv2	pan-cancer	AAC	0.082	0.02
mRNA	ZNF528	CTRPv2	pan-cancer	AAC	-0.12	0.0006
mRNA	ZNF530	CTRPv2	pan-cancer	AAC	-0.12	0.0003
mRNA	ZNF544	CTRPv2	pan-cancer	AAC	-0.089	0.01
mRNA	ZNF549	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	ZNF550	CTRPv2	pan-cancer	AAC	-0.14	0.0001
mRNA	ZNF559	CTRPv2	pan-cancer	AAC	-0.084	0.02
mRNA	ZNF563	CTRPv2	pan-cancer	AAC	-0.097	0.004
mRNA	ZNF57	CTRPv2	pan-cancer	AAC	0.1	0.005
mRNA	ZNF578	CTRPv2	pan-cancer	AAC	-0.12	0.0008

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