5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ADAT2	CTRPv2	pan-cancer	AAC	0.2	9e-07
mRNA	RPS6	CTRPv2	pan-cancer	AAC	0.19	1e-06
mRNA	EEF2	CTRPv2	pan-cancer	AAC	0.18	1e-06
mRNA	RHEB	CTRPv2	pan-cancer	AAC	-0.19	1e-06
mRNA	HAL	CTRPv2	pan-cancer	AAC	0.16	1e-06
mRNA	CREB3L2	CTRPv2	pan-cancer	AAC	-0.17	1e-06
mRNA	RP11-6L6.2	CTRPv2	pan-cancer	AAC	0.16	1e-06
mRNA	CKMT1B	CTRPv2	pan-cancer	AAC	0.18	1e-06
mRNA	HMSD	CTRPv2	pan-cancer	AAC	0.16	2e-06
mRNA	WISP1	CTRPv2	pan-cancer	AAC	0.16	2e-06

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