5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GALM	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	SNX5	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	GOLGA6L6	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	HADHA	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	WNT8B	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	KIF21B	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	GOLGA6L1	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	RP11-229P13.27	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	CARD8	CTRPv2	pan-cancer	AAC	0.16	0.0003
mRNA	KCTD7	CTRPv2	pan-cancer	AAC	-0.13	0.0003

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