5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ARHGDIG	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	COPZ2	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	TRIM22	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	XPC	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	RP11-212D19.4	CTRPv2	pan-cancer	AAC	-0.13	0.0002
mRNA	NEK3	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	MLXIPL	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	GOLGA8T	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	KLHDC2	CTRPv2	pan-cancer	AAC	-0.13	0.0002
mRNA	SERPINB5	CTRPv2	pan-cancer	AAC	0.15	0.0002

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