5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SNF8	CTRPv2	pan-cancer	AAC	-0.082	0.02
mRNA	HS6ST3	CTRPv2	pan-cancer	AAC	-0.08	0.02
mRNA	ITPKB	CTRPv2	pan-cancer	AAC	-0.09	0.02
mRNA	MYEF2	CTRPv2	pan-cancer	AAC	-0.088	0.02
mRNA	PRKX	CTRPv2	pan-cancer	AAC	0.086	0.02
mRNA	SLC35A5	CTRPv2	pan-cancer	AAC	-0.081	0.02
mRNA	BCKDHA	CTRPv2	pan-cancer	AAC	0.085	0.02
mRNA	ZNF524	CTRPv2	pan-cancer	AAC	0.082	0.02
mRNA	RNASE9	CTRPv2	pan-cancer	AAC	-0.077	0.02
mRNA	KLF16	CTRPv2	pan-cancer	AAC	0.08	0.02

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