5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	VAMP1	CTRPv2	pan-cancer	AAC	-0.087	0.01
mRNA	TRIM60	CTRPv2	pan-cancer	AAC	0.081	0.01
mRNA	ZNF132	CTRPv2	pan-cancer	AAC	-0.091	0.01
mRNA	PLCB4	CTRPv2	pan-cancer	AAC	-0.096	0.01
mRNA	NCKAP1L	CTRPv2	pan-cancer	AAC	0.12	0.01
mRNA	NISCH	CTRPv2	pan-cancer	AAC	0.09	0.01
mRNA	ELP3	CTRPv2	pan-cancer	AAC	0.091	0.01
mRNA	PSMB10	CTRPv2	pan-cancer	AAC	0.098	0.01
mRNA	KMT2A	CTRPv2	pan-cancer	AAC	-0.086	0.01
mRNA	CD160	CTRPv2	pan-cancer	AAC	0.083	0.01

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