5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SEMA3G	CTRPv2	pan-cancer	AAC	0.086	0.01
mRNA	CXCR6	CTRPv2	pan-cancer	AAC	0.083	0.01
mRNA	NUFIP2	CTRPv2	pan-cancer	AAC	0.084	0.01
mRNA	UBR7	CTRPv2	pan-cancer	AAC	-0.088	0.01
mRNA	ZNF841	CTRPv2	pan-cancer	AAC	-0.084	0.01
mRNA	KIRREL3	CTRPv2	pan-cancer	AAC	-0.089	0.01
mRNA	RCOR3	CTRPv2	pan-cancer	AAC	0.089	0.01
mRNA	LILRB1	CTRPv2	pan-cancer	AAC	0.088	0.01
mRNA	AIM2	CTRPv2	pan-cancer	AAC	0.086	0.01
mRNA	ORC3	CTRPv2	pan-cancer	AAC	-0.084	0.01

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