5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SPAG9	CTRPv2	pan-cancer	AAC	-0.092	0.01
mRNA	CYP2J2	CTRPv2	pan-cancer	AAC	0.091	0.01
mRNA	ACTN1	CTRPv2	pan-cancer	AAC	-0.097	0.01
mRNA	AMN	CTRPv2	pan-cancer	AAC	0.089	0.01
mRNA	MTCL1	CTRPv2	pan-cancer	AAC	-0.086	0.01
mRNA	EVI5L	CTRPv2	pan-cancer	AAC	-0.09	0.01
mRNA	PTTG1	CTRPv2	pan-cancer	AAC	-0.085	0.01
mRNA	AHDC1	CTRPv2	pan-cancer	AAC	-0.086	0.01
mRNA	NOTCH2	CTRPv2	pan-cancer	AAC	-0.097	0.01
mRNA	C12orf66	CTRPv2	pan-cancer	AAC	0.09	0.01

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