5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GREB1	CTRPv2	pan-cancer	AAC	-0.093	0.01
mRNA	PIM3	CTRPv2	pan-cancer	AAC	0.086	0.01
mRNA	HSPD1	CTRPv2	pan-cancer	AAC	0.087	0.01
mRNA	ELMO2	CTRPv2	pan-cancer	AAC	-0.088	0.01
mRNA	IRF6	CTRPv2	pan-cancer	AAC	0.11	0.01
mRNA	SSSCA1	CTRPv2	pan-cancer	AAC	-0.085	0.01
mRNA	GLCE	CTRPv2	pan-cancer	AAC	0.093	0.01
mRNA	DHX8	CTRPv2	pan-cancer	AAC	0.087	0.01
mRNA	C11orf80	CTRPv2	pan-cancer	AAC	-0.09	0.01
mRNA	FARP1	CTRPv2	pan-cancer	AAC	-0.096	0.01

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