5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	OR2A7	CTRPv2	pan-cancer	AAC	0.098	0.01
mRNA	SLC46A2	CTRPv2	pan-cancer	AAC	-0.086	0.01
mRNA	SEC62	CTRPv2	pan-cancer	AAC	-0.086	0.01
mRNA	RP11-515E23.1	CTRPv2	pan-cancer	AAC	0.086	0.01
mRNA	MTOR	CTRPv2	pan-cancer	AAC	-0.09	0.01
mRNA	TEPSIN	CTRPv2	pan-cancer	AAC	0.091	0.01
mRNA	RAB25	CTRPv2	pan-cancer	AAC	0.11	0.01
mRNA	CHIC2	CTRPv2	pan-cancer	AAC	-0.086	0.01
mRNA	MTPAP	CTRPv2	pan-cancer	AAC	0.093	0.01
mRNA	CDKN2A	CTRPv2	pan-cancer	AAC	-0.086	0.01

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