5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF829	CTRPv2	pan-cancer	AAC	-0.093	0.01
mRNA	SRGN	CTRPv2	pan-cancer	AAC	0.088	0.01
mRNA	PADI4	CTRPv2	pan-cancer	AAC	-0.086	0.01
mRNA	PHKA2	CTRPv2	pan-cancer	AAC	0.092	0.01
mRNA	HS3ST4	CTRPv2	pan-cancer	AAC	0.1	0.01
mRNA	ZSCAN21	CTRPv2	pan-cancer	AAC	-0.089	0.01
mRNA	ZNF337	CTRPv2	pan-cancer	AAC	0.087	0.01
mRNA	ARPC1A	CTRPv2	pan-cancer	AAC	-0.093	0.01
mRNA	RPL18	CTRPv2	pan-cancer	AAC	0.098	0.01
mRNA	CAT	CTRPv2	pan-cancer	AAC	0.088	0.01

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