5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DIAPH2	CTRPv2	pan-cancer	AAC	0.091	0.009
mRNA	BIRC7	CTRPv2	pan-cancer	AAC	-0.092	0.009
mRNA	POLD4	CTRPv2	pan-cancer	AAC	-0.09	0.009
mRNA	DGKQ	CTRPv2	pan-cancer	AAC	0.091	0.009
mRNA	OR1A1	CTRPv2	pan-cancer	AAC	-0.085	0.009
mRNA	ALDH3A2	CTRPv2	pan-cancer	AAC	0.095	0.009
mRNA	MMP23B	CTRPv2	pan-cancer	AAC	-0.088	0.009
mRNA	GJB5	CTRPv2	pan-cancer	AAC	0.11	0.009
mRNA	XPO4	CTRPv2	pan-cancer	AAC	0.093	0.009
mRNA	STMN4	CTRPv2	pan-cancer	AAC	0.1	0.009

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