5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NHLRC1	CTRPv2	pan-cancer	AAC	-0.094	0.009
mRNA	RPL41	CTRPv2	pan-cancer	AAC	0.093	0.009
mRNA	VASN	CTRPv2	pan-cancer	AAC	-0.097	0.009
mRNA	SFTPD	CTRPv2	pan-cancer	AAC	0.086	0.009
mRNA	FGD3	CTRPv2	pan-cancer	AAC	-0.094	0.009
mRNA	FARS2	CTRPv2	pan-cancer	AAC	0.088	0.009
mRNA	MCOLN2	CTRPv2	pan-cancer	AAC	0.094	0.009
mRNA	TPM1	CTRPv2	pan-cancer	AAC	-0.11	0.009
mRNA	CDRT4	CTRPv2	pan-cancer	AAC	0.09	0.009
mRNA	PPIP5K2	CTRPv2	pan-cancer	AAC	-0.095	0.009

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