5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF329	CTRPv2	pan-cancer	AAC	-0.15	1e-05
mRNA	CDRT15L2	CTRPv2	pan-cancer	AAC	0.14	1e-05
mRNA	SLC39A7	CTRPv2	pan-cancer	AAC	-0.16	1e-05
mRNA	DST	CTRPv2	pan-cancer	AAC	-0.16	1e-05
mRNA	ZNF229	CTRPv2	pan-cancer	AAC	-0.16	1e-05
mRNA	TNFRSF1B	CTRPv2	pan-cancer	AAC	0.16	1e-05
mRNA	TNFRSF8	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	FAM126A	CTRPv2	pan-cancer	AAC	-0.17	2e-05
mRNA	JAK3	CTRPv2	pan-cancer	AAC	0.17	2e-05
mRNA	MAGED1	CTRPv2	pan-cancer	AAC	-0.17	2e-05

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