5-FU

Synonyms

Sources	Names Used
GDSC1000	5-Fluorouracil
GRAY	5-FU
CTRPv2	fluorouracil
PharmacoGx	5-FU

External IDs

Database	Identifier
Smiles:	C1=C(C(=O)NC(=O)N1)F
Inchikey:	GHASVSINZRGABV-UHFFFAOYSA-N
Pubchem:	3385

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to 5-FU

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C9orf72	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	PTTG1IP	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	TMEM230	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	RP11-293I14.2	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	GNG12	CTRPv2	pan-cancer	AAC	-0.14	0.002
mRNA	PGRMC2	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	BST2	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	GCNT7	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	SORT1	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	AMY2A	CTRPv2	pan-cancer	AAC	0.11	0.002

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